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912 This is most likely due to the high rate of consanguinity leading to increased autosomal recessive disorders in the region

Warnings If you think you might be pregnant, stop taking this medicine and tell your doctor

Cell Metab 27(6):12121221.e3

Energy changes may take several weeks to develop, and full metabolic benefits typically become more noticeable after 4 to 8 weeks as the body adjusts to treatment

For body weight, SBP, total cholesterol and HDL cholesterol, a recovery rate over 4 years was assumed based on data from the extension part of study STEP 1, where an exponential model was fit to the observed data to derive inputs for the model beyond 1 year (Table S4) [60]