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Although semaglutide had limited effects on hyperglycemia and weight loss, it improved lipid profiles and reduced oxidative stress [86]

Women with PCOS often have insulin resistance, elevated androgens, and metabolic dysfunction that may affect treatment response

[111, 116] the term vitagenes refers to a group of genes that are strictly involved in preserving cellular homeostasis during stress conditions and the vitagene family includes heat shock proteins (HSPs), heme oxygenase-1 (HSP32, HO-1), HSP60 and HSP70, the thioredoxins (Trx)/thioredoxins reductase (TrxR) system and sirtuins

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