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SHMT2 not only was found to be highly expressed in glioblastoma (GBM) (Kim et al., 2015), hepatocellular carcinoma (HCC) (Woo et al., 2016), colorectal cancer (CRC) (Wei et al., 2018), and diffuse large B-cell lymphoma (DLBCL) (Ducker et al., 2017) but also specifically promoted the growth and proliferation of tumor cells when the glycine cleavage system was not functioning properly (Kim et al., 2015)

"We're seeing now that companies are adding fiber to foods, but a lot of the time, they don't add the kind of fiber that's super beneficial for you," Duca says

10.1038/s41586-019-1707-0 17 DongK.LiuB.ChengG.LiY.XieF.ZhangJ.et al (2025)

GLP-1 agonists can help lower inflammation, a common lipedema issue, by improving metabolic health and reducing adipose tissue