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Medicare Advantage beneficiaries are also less likely to receive newer antihyperglycemic therapies with proven outcome benefits in high-risk individuals. They added that these findings reinforce the need for surveillance of long-term outcomes under various Medicare plan structures and for program evaluation to ensure that indicated but more costly care is not stinted among at-risk beneficiaries under managed care approaches

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While GLP-1 medications do not directly increase relaxin, rapid metabolic and hormonal shifts during significant weight loss may create similar effects on connective tissue in some individuals

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