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This matters because combination therapy is not a short-term strategy

Zhao, Q

If approved, orforglipron would be the first oral GLP-1 therapy with efficacy comparable to injectables , potentially redefining obesity and diabetes treatment worldwide

Andrew Lee, clinical spokesperson for the American Academy of Ophthalmology and a neuro-ophthalmologist at Houston Methodist Hospital, said he's had some patients who developed NAION who were taking semaglutide, but the question was always whether this is a causal association or merely an association alone. People with Type 2 diabetes are already at an increased risk for vision problems, including NAION

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