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The most commonly reported events in active arms were mild and transient: injection site reactions in some subcutaneous subjects, occasional headache, and in some oral dosing arms, minor gastrointestinal tolerance issues

Ulanovskaya OA, Zuhl AM, Cravatt BF

By blocking NNMT activity, the compound preserves nicotinamide availability for the NAD+ salvage pathway, leading to 1.2- to 1.6-fold increases in intracellular NAD+ concentrations

Dosing and frequency differ between animals and conditions, so your veterinarian will put together the right protocol for your specific pet or livestock