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In prostate cancer, GLP-1R expression is relatively limited, but metabolic modulation by GLP-1RAs may confer indirect protective effects via inhibition of the PI3K/Akt pathway [341]
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Study Details | NCT06047548 | A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities | ClinicalTrials.gov One of the big buzz words in the GLP-1 space is maintenance dosing
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Patients should be carefully monitored, and the risks weighed against the benefits on a case-by-case basis, particularly when used outside of its original medical context
CLEC7A is activated by -1,3 glucans and regulates a range of cellular responses including phagocytosis, respiratory burst, and enhanced production of cytokines [43]
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