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Heat provides energy that can cause the amino acid bonds to vibrate and break, denaturing the peptide

J Trauma Stress 33(5):699708 He S, Hasler BP, Chakravorty S (2019) Alcohol and sleep-related problems

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This finding suggested that the free thiol groups in glutathione effectively cleave the disulfide bonds within the framework, thereby facilitating the degradation of the MSN-ss-SA structure and promoting the release of SA and bioavailable silicon

Mottet, A