Among the ROS, hydroxyl is the most reactive radical, which reacts with lipids, proteins, nucleic acids, and carbohydrates
Amino acids V12 (putative oxyanion hole), F112 (active site architecture), N108 (flavonoid binding) and C13 (GSH stabilization) were fully randomized by site saturation mutagenesis (NNK codons), and the created Pt GSTF8 variants were tested for conversion of flavan-3,3,4-triol ( 4 ) to cyanidin ( 8 ), and for their GSH-transferase activity towards CDNB ( 5 ) as a control of catalytic competence
J Ind Microbiol Biotechnol 42:537542
It was found that this was due to high concentration of the flavonoids and other polyphenolic substances (Jahan et al., 2018)
B-Complex Vitamins A group of vitamins that contribute to energy metabolism, brain function and nervous system health