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In addition, there is evidence in the literature, including meta-analyses, comparing the effectiveness of combinations of physical and dietary interventions

(2020) 10:E758

Notably, the proportion of CD3 + and CD8 + dual-positive cytotoxic T cells was significantly higher in the combination therapy group (5.64 1.72%)14.8-fold that in the anti-PD-1 group (0.38 0.11%) and 3.97-fold that in the monotherapy group (1.42 0.59%) (Fig