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The heterogeneity in study designs, populations, and NSW definitions complicates direct comparisons

Studies have shown that EVs secreted by MenSCs can function as exogenous ROS scavengers, thereby reducing the dependence of embryos from aged female mice on endogenous antioxidant proteins such as superoxide dismutase 1 (SOD1) and glutathione peroxidase 1 (GPX1), ultimately improving IVF outcomes (Marinaro et al., 2018)

PMID 8930132

doi: 10.1007/s11010-019-03667-9 5 Di MarzoNChisciEGiovannoniR

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