18 investigated the foliar application of spermidine, spermine, and putrescine (at 0.5, 1, and 2.5 mM) on secondary metabolites and antioxidant activity of potted Calendula officinalis flowers, reporting significant increases in total phenolic content, flavonoids, and antioxidant capacity
The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting
3-month plan: $477 total All vials will ship together
Wegovy, the higher-dose version specifically approved for weight management, received TGA approval in Australia in 2023
doi: 10.1071/ZO01038 38 Varo-GhiuruF.MicleaI.HettigA.LadoiI.MicleaV.EgerszegiI.et al