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1), structurally modeled on Epithalamin, a natural extract derived from the pineal gland of cattle [1, 4]

Genome-wide haploid and clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 based screening revealed that two membrane remodeling enzymes, acyl-CoA synthetase long chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3), were important drivers of ferroptosis (Schwarz and Foltz, 1999)