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If you are one of our patients and are experiencing persistent or severe side effects while taking GLP-1 medications, you should speak to your Mochi Health provider to discuss switching to a different medication or adjusting your dose
Enrollment reaches 2.3 million to 3.9 million
The shift is significant, but it comes with specific eligibility requirements, covered medications, and limitations worth knowing before you assume you qualify for Wegovy or Zepbound

Food and Drug Administration (2024) Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes, The New England Journal of Medicine (2024) Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials, The Lancet Diabetes & Endocrinology (2025) Phase 3 trial of semaglutide in metabolic dysfunctionassociated steatohepatitis, The New England Journal of Medicine (2025) Tirzepatide for metabolic dysfunction-associated steatohepatitis with liver fibrosis, The New England Journal of Medicine (2024) A phase 2 randomized trial of survodutide in MASH and fibrosis, The New England Journal of Medicine (2024) Semaglutide in patients with heart failure with preserved ejection fraction and obesity, The New England Journal of Medicine (2023) Tirzepatide for heart failure with preserved ejection fraction and obesity, The New England Journal of Medicine (2024) Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial, The Lancet (2025) Once-weekly semaglutide in adults with alcohol use disorder, JAMA Psychiatry (2025) Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial, The Lancet (2026) Comparative efficacy of pharmacological interventions on metabolic and hormonal outcomes in polycystic ovary syndrome: a network meta-analysis of randomized controlled trials, BMC Womens Health (2025) Effectiveness and tolerability of liraglutide as add-on treatment in patients with obesity and high-frequency or chronic migraine: A prospective pilot study, Headache (2025) GLP-1R agonist liraglutide attenuates pain hypersensitivity by stimulating IL-10 release in a nitroglycerin-induced chronic migraine mouse model, Neuroscience Letters (2023) Recent advances and therapeutic benefits of glucagon-like peptide-1 (GLP-1) agonists in the management of type 2 diabetes and associated metabolic disorders, Cureus (2024) Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimers disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials, The Lancet (2026) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice
