Retrieved 23 August 2025
Although Ex4 acts in the brain, the neurochemical mechanisms underlying this activation are not fully elucidated

What You Get 4 or 8-Week Medication Supply (Semaglutide or Tirzepatide, if prescribed by a licensed healthcare provider) Personalized Virtual Consultation with a licensed provider to assess your eligibility and goals All-In-One Injection Kit for injection programs, designed for safety and ease of use (if prescribed) Direct Home Delivery of your medication, for a convenient and seamless experience Ongoing Medical Support including healthy eating information, WhatsApp education, and text access through a patient portal Medical Eligibility Required Semaglutide and Tirzepatide cannot be prescribed to individuals with the following conditions: BMI under 27, eating disorders, Type 1 diabetes, gallbladder disease, substance abuse, recent bariatric surgery (within the past 6 months), pancreatitis or history of recurrent pancreatitis while taking a GLP-1 medication, medullary thyroid cancer, current pregnancy or breastfeeding, plans to become pregnant, diabetic retinopathy, multiple endocrine neoplasia type 2 (MEN2) or family history of MEN2, serious gastrointestinal disorders, or history of allergic reaction to Tirzepatide or Semaglutide

Always inform your PlexusDx provider about any supplements before starting or during GLP-1 therapy
The other two, erythrohydrobupropion and threohydrobupropion, have half-lives of roughly 33 and 37 hours