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The failure was related to efficacy, not major safety concerns

This peptide enhances angiogenesis, which improves blood flow to damaged area, which provides better circulation with more oxygen and nutrients needed to heal inflamed areas

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doi: 10.1038/s41467-021-25552-0

Nrf2, a member of the capncollar family of basic regionleucine zipper transcription factors involved in transcription of antioxidant genes in response to xenobiotic stress, is also a critical regulator of cellular oxidative stress in sepsis (Kolls, 2006) and a regulator of exacerbated proinflammatory cytokine release (cytokine storm) and loss of T lymphocytes (leukopenia) that characterize the most aggressive presentation of SARS-CoV-2-mediated COVID-19 infection (Kobayashi et al., 2016