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The use of GSH precursors like N-acetyl cysteine, enhancers of nuclear factor erythroid 2-related factor 2 (Nrf2) like sulforaphane, melatonin, and many more molecules involved in antioxidant defense were proposed as supplementation of other idiopathic pulmonary fibrosis therapies (130)

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The research priorities are clear: Phase I safety trials in healthy volunteers must be completed, followed by Phase II efficacy trials for specific conditions if safety is confirmed