These findings suggest a novel therapeutic pathway for IIH management, where GLP-1R agonists may offer dual benefits in weight reduction and headache relief [58]
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PCSK1 or PC1/3) is expressed in GCG + cells in the brain and the intestine, and cleavage of Gcg by PCSK1 results in the liberation of GLP-1, GLP-2, glicentin, oxyntomodulin, and IP2 (Figure 1) [[147], [148], [149], [150]]
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