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Nat Commun (2017) 8:16114

Good nutritional status is known to be important for normal cognitive functioning, but the role of diet in the prevention of age-related cognitive decline is not well understood

L- amino acids are essential for protein synthesis and energy production, and mammals (including humans) synthesize amino acids almost exclusively in the L- configuration.75 In supplements, L- or D- may be more informed by bioavailability, as the body may better absorb the L form of one amino acid or the D form of another