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Gastroenterol Clin North Am 52(2):363380 Arterburn DE, Telem DA, Kushner RF, Courcoulas AP (2020) Benefits and risks of bariatric surgery in adults: a review
Natural GLP-1R is known to be N-glycosylated at positions 63, 82 and 115kDa(PMID: 36769142)
The transcellular route refers to either transporter- or receptor-medicated access that across the BBB
Therefore, in GLP-1R KO mice, compensation mechanisms of other receptors may exist to balance the cAMP-mediated downstream signaling pathway to maintain normal survival and activities of the GLP-1R KO mice
PMC 4767408
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