Whats happening: Collagen remodeling is accelerating, the extracellular matrix is being restructured with new collagen fibers
2001 61(9):3599 - 3603 Subcommittee on the Tenth Edition of the Recommended Dietary Allowances, Food and Nutrition Board, Commission on Life Sciences, National Research Council
In: DiakonovaPM, editor
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167,168 In hepatocytes, elevated lipid load and insulin resistance increase mitochondrial -oxidation activity, accompanied by electron leakage and respiratory chain disruption, resulting in substantial ROS production, which exacerbates lipid peroxidation, autophagic dysfunction, and pyroptosis