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The low molecular weight peptides (~10 kDa) can cross the blood-brain barrier, theoretically delivering neurotrophic support directly to neurons

Krebs LT, Kramar EA, Hanesworth JM, Sardinia MF, Ball AE, Wright JW, and Harding JW (1996) Characterization of the binding properties and physiological action of divalinal- angiotensin IV, a putative AT4 receptor antagonist

(AT1A/), AT1A receptor knockout mice

Feeling of activation and relaxation

These extracts support fibroblast collagen production, inhibit matrix metalloproteinase activity, and protect keratinocytes from UV-induced apoptosis, thereby reducing the appearance of wrinkles and improving skin elasticity