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A few practical concerns hang around with compounded products: The active ingredient may come from facilities not registered with the FDA, with variable purity Some compounded versions use semaglutide salts (semaglutide sodium, semaglutide acetate) that aren't the same molecule studied in the STEP and SUSTAIN trials

One compound that has been shown to drastically affect this process is carnitine

Compounding pharmacies must also perform suitability and sterility testing