The STEP 1 extension study showed that patients regained approximately two-thirds of lost weight within one year of stopping treatment
Vadevoo S, Gurung S, Khan F, Haque M, Gunassekaran G, Chi L, et al
However, the rapid results from Phentermine are often temporary if not supported by lifestyle changes
7.6.1 Strategic research priorities Future research should prioritize expanding multi-omics approaches for comprehensive exposure assessment, investigating cumulative and mixture effects to refine risk predictions, validating transgenerational epigenetic inheritance in human cohorts, developing targeted interventions for mitigating EED-induced reproductive damage, and establishing international regulatory standards for exposure limits and safety assessment
Mechanism of Action in Research Models GIP receptor activation is studied in the context of incretin signaling, glucose-responsive pathways, and insulin physiology areas relevant to type 2 diabetes research models