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Indeed, even yeast only lacking Trx1 are severely compromised in their ability to synthesize DNA during S phase, resulting in growth arrest [92, 93]

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These advancements position microneedle technology as a transformative approach for delivering GLP-1 receptor agonists, offering the potential to improve therapeutic adherence, minimize systemic side effects, and support decentralized care models for diabetes management [43]

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Other adverse effects consistent with this drug class include: Increased resting heart rate : Both GLP-1 and glucagon receptor agonism can raise resting heart rate