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Although it has been reported that the risk of EWDR is increased by faster or more effective lowering of HbA 1c in individuals treated with insulin or a sulfonylurea [14, 25], in our study reduction in HbA 1c was not independently associated with increased odds of the PDR endpoint

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This condition can also be caused by fatty liver disease, alcoholic liver disease, viral infections, including hepatitis B or C, and certain inherited genetic conditions

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