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2.3 Molecular mechanisms of iron-associated brain disorders The underlying mechanisms linking aging, neurodegeneration, and iron accumulation are not yet fully understood

The strain is also reported to reduce the oxidative stress markers in blood and urine in humans [102]

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Hardwick RN, Fisher CD, Canet MJ, Lake AD, Cherrington NJ (2010) Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease

The most recent review on intranasal chelation was published in 2021 by Farr and Xiong, summarizing a decade of preclinical and translational studies on intranasal DFO in neurodegenerative and cerebrovascular conditions (Kosyakov et al., 2021