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Guidelines: the 2023 International PCOS Guideline positions GLP-1RAs as practical weight-loss tools for obese women with PCOS but emphasizes that they must be used within a framework of continuous, effective contraception throughout the treatment period, and should not be considered a routine intervention for weight or metabolic management during pregnancy (17)

There are no links between changes in circulating markers and muscle function or volume

The consent form discloses that in some cases the provider may be a nurse practitioner or physician assistant rather than a physician

More drugs of this kind but made from smaller molecules (and cheaper to produce) are in the works, including two of the new Ozempic pills, orforglipron and danuglipron