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Glutathione peroxidase-1 activity, atherosclerotic burden, and cardiovascular prognosis

Studies in animal models with gut microbiota depletion have shown increased plasma tryptophan, elevated brain serotonin concentrations, and reduced kynurenine pathway activity, all of which normalize following microbiota restoration (229231)

Summary of key findings:(4) Stress Markers: Neither L-theanine nor L-tyrosine significantly reduced physiological stress indicators such as salivary alpha-amylase, secretory immunoglobulin A, heart rate, or state anxiety scores during the stress challenge

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Bossowski A, Moniuszko M, Idkowska E, Grubczak K, Singh P, Bossowska A, Diana T, Kahaly GJ