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The notion that reduced GLP-1 concentrations would result in a reduction of the prokinetic actions of GLP-1 in the colon (27), causing constipation and abdominal pain, was further supported by the correlation between this and the intensity of abdominal discomfort (28)

They should also be made aware of the increased risk of heart disease and retinopathy that may be associated with the drug

Ozempic Ozempic is FDA-approved and indicated for: Improving blood sugar control in adults with type 2 diabetes, alongside diet and exercise Reducing the risk of major cardiovascular events (like heart attack and stroke) in adults with type 2 diabetes who also have cardiovascular disease It may also be prescribed off-label for weight loss

Whether its due to side effect intolerance or having reached the maximum dose, you need a plan of action

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