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Glutathione plays a very important part in Phase II detoxification
The types and focus of these strategies (often called interventions) are summarized in Table 13
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They may involve thiol-disulfide exchange between protein thiol groups and GSSG, perhaps catalyzed by certain GRX, occur through conversion of cysteine thiol groups to thiyl radicals or sulfenic acids, or be mediated by GSNO (Dixon et al., 2005