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The results showed that the terminal body weight of ob/ob-GAN NASH mice increased to 70.01 1.11 g, equivalent to a gain of 9.25 1.09% relative to the initial weight

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Methods: After confirming that berberine can lower blood glucose and improve insulin resistance in db/db mice, the identity maintenance, proliferation and apoptosis of islet cells were detected by immunohistochemistry and immunofluorescence