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For the full MOTS-c evidence review , see our comprehensive guide

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However, extensive studies regarding the mechanistic importance of p53 acetylation in tumor suppression are needed to determine the contributions of these acetyltransferases to the control of p53-mediated ferroptosis

This was coupled with enhanced interactions at the top of TM1 and distinct and more sustained interactions within TM7 (Figure 6, Supplemental Table 3)