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Many gastrointestinal disorders may determine recurrent vomiting due to bowel obstruction (malrotation with volvulus, duplication cyst, and intermittent intestinal intussusception, chronic intestinal pseudo-obstruction), allergic or inflammatory process (food allergy, eosinophilic esophagitis, gastritis, duodenitis, hepatitis, biliary tract dysmotility, pancreatitis, pancreatic pseudocyst, appendicitis, peptic disease, inflammatory bowel disease)

It works in a glucose-dependent way, meaning its insulin-related effect is tied to elevated blood sugar

The observed impact of oral semaglutide on cardiovascular outcomes underscore its potential to address a critical unmet need in type 2 diabetes and cardiometabolic disease management.

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Curr Nutr Rep 11 , 618642 (2022)