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The tricky part with weight loss is that you're not just losing fat
Studies show that growth hormone levels decline after mid-thirties and affect various metabolic processes including fat metabolism, muscle mass maintenance and energy regulation
however, the continuous accumulation of senescent cells, through the secretion of pro-inflammatory molecules known as the senescence-associated secretory phenotype (SASP), ultimately leads to chronic inflammation, tissue dysfunction, and age-related diseases
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there was a trend-level positive correlation with acyl-ghrelin AUC as well ( r = 0.40, p = 0.07) (Fig
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