Healthy male subjects, age 2055 years, with good glycemic control [HbA 1c 6.0% (42 mmol/mol) or less]
The positive effects of both treatments on weight loss demonstrated previously [11,12,13,14,15,16,17,18,19,20, 24] highlight the importance of newer agents among current pharmacological options, compared with older, standard approaches for type 2 diabetes that may increase or have little effect on weight [46]
[DOI] [PubMed] [Google Scholar] 85.Hunter K., Hlscher C
One case involved a middle-aged patient with type 2 diabetes and major depressive disorder, who experienced significant weight loss and improved glycemic control on Semaglutide, alongside a marked improvement in depressive symptoms with Zoloft
Animal work indicates tissue healing and blood-vessel impacts, but animals metabolize drugs differently and dosing frequently exceeds human use