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Mice were continuously measured for lung metastases using bioluminescence imaging once a week until reaching end point, or poor body condition in accordance with animal welfare guidelines

This was emphasised in the CANTOS trial, in which a monoclonal antibody targeting IL-1 in individuals with established atherosclerotic CVD and evidence of systemic inflammation reduced the risk of major adverse cardiovascular events (MACE) by 1517%, an effect that was likely to be mediated by reductions in serum CRP concentrations [80, 81]

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(2015) 309:C16978

Environ Sci Technol 33:27102714 Filho DW, Giulivi C, Boveris A (1993) Antioxidant defences in marine fishI