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This interaction triggers c-Met phosphorylation and activates downstream signaling cascades including the PI3K/AKT and MAPK/ERK pathways, which are fundamental to neuronal survival, dendritic arborization, and synapse formation

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Int J Nurs Stud (1994) 31(4):391401

Product information documents contain: Treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise: For study results with respect to combinations, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4.4, 4.5 and 5.1.