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Once injected, B12 enters the bloodstream directly without requiring stomach acid, intrinsic factor (a protein necessary for B12 absorption), or healthy intestinal function

Anemia can lead to weakness and fatigue

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Diabetes Obes Metab 23(8):18061822 Brock C, Hansen CS, Karmisholt J, Moller HJ, Juhl A, Farmer AD et al (2019) Liraglutide treatment reduced interleukin-6 in adults with type 1 diabetes but did not improve established autonomic or polyneuropathy

Vegetarians or vegans If youre diet doesnt consist of the proper amounts of meat, fish and eggs Over age 50 Pregnant or breastfeeding Cigarette smokers You take medications for heartburn or take potassium supplements If youve had part of your stomach surgically removed or banded Chronic Fatigue Syndrome Why is a lack of B12 of such concern