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aaos-annualmeeting-presskit.org/2026/research-news/studies-explore-glp-1-receptor-agonist-use-and-its-impact-on-long-term-musculoskeletal-health Yaribeygi H, Maleki M, Jamialahmadi T, Sahebkar A

CGA treatment improves motor coordination in a mouse model of PD induced by MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydopyridine) [77]

In terms of mechanisms, following release, GH binds to its receptor leading to the recruitment and phosphorylation of Janus kinase 2 (JAK2) and its most recognized downstream target, signal transducer and activator of transcription 5 (STAT5) (Jrgensen et al., 2006)

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