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The peptide stack calculator on SeekPeptides can help you explore how different compounds interact, though any combination protocol should be developed with a qualified healthcare provider

Extracellular fluid volume expansion uncovers a natriuretic action of GLP-1: a functional GLP-1renal axis in man

Step 2: Reduce (if holding does not resolve it)

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Other medications commonly prescribed alongside GLP-1 therapy may contribute to erectile difficulties: Antihypertensives : Beta-blockers and thiazide diuretics are recognised causes of ED Antidepressants : Selective serotonin reuptake inhibitors (SSRIs) frequently impair sexual function 5-alpha-reductase inhibitors : Finasteride and dutasteride for prostate conditions can affect sexual function Antipsychotics : Can impact sexual function through various mechanisms Opioids : May reduce testosterone levels and affect sexual desire and function Spironolactone : Can cause hormonal effects that impact erectile function The relationship between statins and erectile function is complex, with mixed evidence