Wegovy is FDA-approved for chronic weight management and reducing the risk of cardiovascular events in adults with cardiovascular disease
Additionally, adipose (fat) tissue is a source of peripheral oestrogen synthesis via the conversion of androgens by the enzyme aromatase
Over the duration of 10 months, attenuation signals, markers related to obesity (weight, body mass index (BMI), waist circumference), lipids (LDL, triglycerides), inflammation (CRP, IL-6, ESR) and glycemic control (hbA1C) were reduced
Important safety considerations include: Hypoglycaemia risk increases when Ozempic is used in combination with insulin or sulphonylureas
Glucagon-like peptide-1 suppresses advanced glycation end product-induced monocyte chemoattractant protein-1 expression in mesangial cells by reducing advanced glycation end product receptor level