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Nature

Glutathione-S-transferase (GSTP) that participates in the conjugation of GSH to reactive cysteines (S-glutathionylation) seems to play an important role in idiopathic pulmonary fibrosis lung fibrogenesis, since GSTP immunoreactivity is increased in the lungs of idiopathic pulmonary fibrosis patients, notably within type II epithelial cells (128, 129)

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Most trials reported either no or minimal GSH adverse effects, but all had treatment durations of a few doses (IV) or 4 - 12 weeks