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However, due to concerns pertaining to chemical-induced toxicity, the imperative arises to devise innovative strategies for precise GR targeting Houttuynia cordata , recognized for its potential anticancer attributes (Kim et al., 2017), presents an appealing avenue, owing to its status as a naturally occurring repository of phytochemicals that exhibit diminished toxicity in comparison to synthetic counterparts
In addition, casecontrol studies integrating microbiome profiling with systemic immune markers have demonstrated correlations between altered microbial genera and elevated pro-inflammatory cytokines (e.g., IL-6, IFN-, TNF-), supporting a link between gut dysbiosis and systemic immune activation in PD [197]
Oxidative stress mediated mitochondrial damage plays roles in pathogenesis of diabetic nephropathy rat
Initial fitting was done using Namdinator (53) and the ISOLDE plugin (54) of ChimeraX (55)
