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In vitro experiments demonstrated that the LOXL1 protein notably translocated to the cell membrane or extracellular space following transient transfection of hepatic stellate cells with the LOXL1 G153D mutant plasmid

doi: 10.1152/ajplung.1993.265.4.L374 158 GolponHAPuechnerAWelteTWichertPVFeddersenCO

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In normoglycemic, non-obese rabbits , liraglutide significantly inhibited atherosclerosis progression, with meaningful reductions in percent atheroma volume, plaque macrophage content, cathepsin activity, and systemic CRP