Directions for Future Research: Investigations should focus on confirming the efficacy of tirzepatide in type 1 diabetes, elucidating the neuroprotective potential of GLP-1/GIP dual agonists, optimizing perioperative protocols, and facilitating the clinical translation of novel multi-receptor agonists
If a patient cannot maintain hydration for more than 24 hours, our escalation pathway requires an immediate suspension of treatment and a clinical review to protect the biological health of the kidneys
It works by producing short-chain fatty acids that stimulate colonic motility
We provide digital tools such as appointment reminders, educational resources, and access to virtual support, helping patients stay informed and engaged in their care
By using a reducible disulfide linker, we built in a redox-sensitive release mechanism to facilitate intracellular release of the unmodified NMDA receptor antagonist, enabling the combined cellular actions of GLP-1 receptor agonism and NMDA receptor antagonism