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Large IV or oral doses of ascorbic acid have caused hemolytic anemia in some patients with G6PD deficiency (glucose-6-phosphate dehydrogenase deficiency)

The rats were maintained in individual cages, under controlled temperature, humidity and illumination conditions, with water and diet ad libitum for eight weeks

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It has been verified that inhibitory molecules, such as PD1, CTLA4, Tim3, and 2B4, are upregulated on exhausted HBV-specific T cells, which contribute to HBV persistence (2830)