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It is therefore possible that high cholesterol might impact on the capacity of the GLP-1R to regulate mitochondrial and beta cell function via altered expression and interaction with cholesterol regulatory enzymes, hindering the insulin secretion potentiation effect of the receptor

doi: 10.1093/jn/134.3.489 12

doi: 10.1007/s13300-015-0127-x 67 MiambresIPrezA

How long should DPP-4 inhibitors be discontinued before starting GLP-1 analogues?

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