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doi: 10.2165/11586000-000000000-00000 89 GossyeH.EngelborghsS.Van BroeckhovenC.van der ZeeJ

Although reduced caloric intake via activation of neuronal GLP-1R contributes to the weight loss effect of these drugs (2,3), many studies assessing the effect of GLP-1R agonists on food intake in rodents have focused on acute (24 h) timelines during which nausea/visceral illness effects are predominant (4,5)