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Ozempic, Wegovy, and Mounjaro are new drugs

The substance used must be the subject of an FDA-approved drug, on the USP/NF, or on a list FDA maintains of bulk substances permitted for compounding

For patients also taking insulin or sulfonylureas, medication adjustments may be necessary to prevent hypoglycemia if food intake decreases significantly

A proposed molecular mechanism of MSG-induced ROS production is that chronic MSG exposure increases the production of Glutamate which may raise the activity of one of the potential ROS generators like -ketoglutarate dehydrogenase in the rat kidney